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Carlos León Canseco

Imagen de Carlos León Canseco

Professor Carlos León Canseco

Graduated in Chemical Engineering, he completed his Doctoral Thesis (CSIC-UAM) as a beneficiary of a predoctoral scholarship from the Community of Madrid, based on the development of genomic, proteomic and metabolomic methods for the characterization of genetically modified organisms. This doctoral thesis was awarded the Extraordinary PhD Prize of the UAM in 2010. Later, he worked as a junior researcher at the University of Seville, with a contract associated with a project in collaboration with the company Abengoa, consisting of the protein characterization of fungi for the production of bioethanol. Since 2012, he carried out a postdoctoral stay of 2 years and 3 months at the University of California-Davis, dedicated to the development of bioinformatic methods for metabolomic analysis to determine the lipid profile in blood and urine samples of patients with Type II Diabetes, collaborating closely with the West Coast Metabolomics Center, a world reference center in this type of analysis.

After finishing his stay in the USA, he joined the Tissue Engineering and Regenerative Medicine (TERMeG) group in the UC3M as a beneficiary of a postdoctoral contract in the Department of Bioengineering and Aerospace Engineering. He has been a Visiting Professor at UC3M for the past six years and teaches classes in the Biomedical Engineering degree and in the Master in Management and Development of Biomedical Technologies. He is the coordinator of two Master courses (Omic Technologies and Emerging Technologies), and of 2 undergraduate courses (Biological Systems and Synthetic and Systems Biology), receiving in all of them a very positive evaluation in student surveys. His capacity to train students has been reflected in the direction of 6 final degree projects and more than 10 final master projects, as well as in the development of 5 Teaching Innovation projects, as well as participation in seminars, workshops, committees and institutional representation of the university.

His research activity lays mainly in the field of omic technologies and includes 19 research articles in the first quartile of his area (10 of them in the first decile), and 2 in the second quartile. In addition, he is co-author of 4 book chapters and more than 25 communications in national and international conferences and is a member of the editorial committee of a journal in the bioinformatics area and a censor of numerous journals in the area of ​​analytical chemistry. He is part of the TERMeG team in numerous research projects, focusing his research career on the study and transcriptomic and metabolomic analysis of genodermatosis, with a predisposition to tumor development, such as epidermolysis bullosa, Kindler's syndrome or xenoderma pigmentosum. His contribution to the group in the development and use of bioinformatic methods for the analysis of massive biological data obtained with omic technologies has been fundamental for the description of a genetic signature common to three genodermatoses with cancer predisposition and for the current study of the therapeutic mechanisms of mesenchymal stem cells for the treatment of RDEB in the context of a clinical trial.